Transcription factors, coregulators, and epigenetic marks are linearly correlated and highly redundant.
PLoS ONE
DOI: 10.1371/journal.pone.0186324.
Published 7 December 2017.
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CIRCLE-seq: a highly sensitive in vitro screen for genome-wide CRISPR–Cas9 nuclease off-targets
Nature Methods
DOI: 10.1038/nmeth.4278.
Published Online 1 May 2017.
Full Text PDF.
Supplemental Materials.
Open-source guideseq software for analysis of GUIDE-seq data
Nature Biotechnology
34(5):483
DOI: 10.1038/nbt.3534.
Published 1 May 2016.
Full Text PDF.
Supplemental Materials.
Broadening the targeting range of Staphylococcus aureus CRISPR-Cas9 by modifying PAM recognition
Nature Biotechnology
33(12):1293-1298
DOI: 10.1038/nbt.3404.
Published 2 November 2015.
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Supplemental Materials.
Engineered CRISPR-Cas9 nucleases with altered and improved PAM specificities
Nature
523(7561): 481-485.
DOI: 10.1038/nature14592.
Published 22 June 2015.
Full Text PDF.
Supplemental Materials.
Dimeric CRISPR RNA-guided FolkI-dCas9 nucleases (RFNs) directed by truncated gRNAs for highly specific genome editing
Human Gene Therapy
26(7): 425-431 (2015).
DOI: 10.1089/hum.2015.084.
Published 12 June 2015.
Full Text PDF.
Replacing Uridine with 2-Thiouridine Enhances the Rate and Fidelity of Nonenzymatic RNA Primer Extension
Journal of the American Chemical Society
137(7): 2769−2775 (2015).
DOI: 10.1021/jacs.5b00445.
Published 5 February 2015.
Full Text PDF.
Supplemental Materials.
GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases
Nature Biotechnology
33(2): 187–197 (2015).
DOI: 10.1038/nbt.3117.
Published 16 December 2014.
Full Text PDF.
Supplemental Materials.